Effect of raloxifene on sexual function in postmenopausal women
| العنوان: | Effect of raloxifene on sexual function in postmenopausal women |
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| المؤلفون: | L Nachtigall, B. Kessel, Suresh Siddhanti, Amy Rosen, Anna K. Parsons, Leo Plouffe |
| المصدر: | Climacteric. 6:248-256 |
| بيانات النشر: | Informa UK Limited, 2003. |
| سنة النشر: | 2003 |
| مصطلحات موضوعية: | Gynecology, medicine.medical_specialty, business.industry, Genitourinary system, Obstetrics and Gynecology, General Medicine, medicine.disease, Placebo, Vaginal estrogen, law.invention, Atrophy, Randomized controlled trial, law, Internal medicine, medicine, Raloxifene, Vaginal atrophy, business, Sexual function, medicine.drug |
| الوصف: | Objective: To determine the effects of raloxifene on sexual function in postmenopausal women with pre-existing vaginal atrophy treated with vaginal estrogen cream. Methods: A total of 187 naturally postmenopausal women, 42-80 years of age, with signs of genitourinary atrophy were enrolled in this 6-month, multicenter, parallel-group study. Subjects were randomized to oral raloxifene HCl 60 mg daily or matching placebo; the same subjects were also randomized to receive one application of either vaginal conjugated estrogen cream 0.5 g twice weekly for 6 months or non-hormonal vaginal moisturizer twice weekly for 3 months, followed by conjugated estrogen cream for 3 months. Both investigators and subjects were masked to the identity of the oral medication. The vaginal preparations were administered in an open-label fashion. The Sexual Activity Questionnaire (SAQ) was administered at baseline and at 3 and 6 months. Safety was assessed throughout the study. Results: A total of 102 women were sexually active at... |
| تدمد: | 1473-0804 1369-7137 |
| DOI: | 10.1080/cmt.6.3.248.256 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::76e56d3aade0786a95b8b55be0fcd284 https://doi.org/10.1080/cmt.6.3.248.256 |
| رقم الانضمام: | edsair.doi...........76e56d3aade0786a95b8b55be0fcd284 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14730804 13697137 |
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| DOI: | 10.1080/cmt.6.3.248.256 |