Oral Terbinafine and Itraconazole Treatments against Dermatophytes Appear Not to Favor the Establishment of Fusarium spp. in Nail
| العنوان: | Oral Terbinafine and Itraconazole Treatments against Dermatophytes Appear Not to Favor the Establishment of Fusarium spp. in Nail |
|---|---|
| المؤلفون: | Olympia Bontems, Florence Baudraz-Rosselet, Julie Verrier, Michel Monod |
| المصدر: | Dermatology. 228:225-232 |
| بيانات النشر: | S. Karger AG, 2014. |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | Fusarium, medicine.medical_specialty, Nail Infection, biology, Itraconazole, food and beverages, Dermatology, biology.organism_classification, Microbiology, medicine.anatomical_structure, Pharmacotherapy, medicine, Nail (anatomy), Terbinafine, Trichophyton, High incidence, skin and connective tissue diseases, medicine.drug |
| الوصف: | Background: Fusarium onychomycoses are weakly responsive or unresponsive to standard onychomycosis treatments with oral terbinafine and itraconazole. Objective: To examine whether the use of terbinafine and itraconazole, which are highly effective in fighting Trichophyton onychomycoses, could be a cause of the high incidence of Fusarium nail infections. Methods: Polymerase chain reaction methods were used to detect both Fusarium spp. and Trichophyton spp. in nails of patients who had either received treatment previously or not. Results: No significant microbiological differences were found between treated and untreated patients. In 24 of 79 cases (30%), Fusarium spp. was detected in samples of patients having had no previous antifungal therapy and when Trichophyton spp. grew in culture. Conclusion: Oral terbinafine and itraconazole treatments do not appear to favor the establishment of Fusarium spp. in onychomycosis. |
| تدمد: | 1421-9832 1018-8665 |
| DOI: | 10.1159/000357764 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::7184b6487215a51655561606de906fdf https://doi.org/10.1159/000357764 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi...........7184b6487215a51655561606de906fdf |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14219832 10188665 |
|---|---|
| DOI: | 10.1159/000357764 |