Balancing gene transfection and cytotoxicity of nucleic acid carriers with focus on ocular and hepatic disorders: evaluation of hydrophobic and hydrophilic polyethyleneimine derivatives
| العنوان: | Balancing gene transfection and cytotoxicity of nucleic acid carriers with focus on ocular and hepatic disorders: evaluation of hydrophobic and hydrophilic polyethyleneimine derivatives |
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| المؤلفون: | Fernando A. de Oliveira, Lindomar J. C. Albuquerque, Michelle Nascimento-Sales, Marcelo A. Christoffolete, Ismael C. Bellettini, Fernando C. Giacomelli |
| المصدر: | Journal of Materials Chemistry B. 11:4556-4571 |
| بيانات النشر: | Royal Society of Chemistry (RSC), 2023. |
| سنة النشر: | 2023 |
| مصطلحات موضوعية: | Biomedical Engineering, General Materials Science, General Chemistry, General Medicine |
| الوصف: | This investigation highlights that ocular and hepatic gene delivery can be potentialized by using small hydrophobic moieties along with lactose domains, and principally, succinic acid conjugated to polyethylenimine chains. |
| تدمد: | 2050-7518 2050-750X |
| DOI: | 10.1039/d3tb00477e |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::6dbb0d534457c1c721e7bc9c8141efe3 https://doi.org/10.1039/d3tb00477e |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi...........6dbb0d534457c1c721e7bc9c8141efe3 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20507518 2050750X |
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| DOI: | 10.1039/d3tb00477e |