Association of the use of diabetes technology with HbA1c and BMI‐SDS in an international cohort of children and adolescents with type 1 diabetes: The SWEET project experience
| العنوان: | Association of the use of diabetes technology with |
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| المؤلفون: | Alexander J. Eckert, Antje Herbst, Carmel E. Smart, Claudio Maffeis, Pravesh K Guness, Michael Witsch, Marco Marigliano |
| المصدر: | Pediatric Diabetes. 22:1120-1128 |
| بيانات النشر: | Hindawi Limited, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Insulin pump, Type 1 diabetes, Pediatrics, medicine.medical_specialty, endocrine system diseases, business.industry, Endocrinology, Diabetes and Metabolism, nutritional and metabolic diseases, Disease, medicine.disease, chemistry.chemical_compound, chemistry, Diabetes mellitus, Metabolic control analysis, Pediatrics, Perinatology and Child Health, Cohort, Internal Medicine, Medicine, Glycated hemoglobin, business, Glycemic |
| الوصف: | Objective To examine the association between the use of diabetes technology [insulin pump (CSII), glucose sensor (CGM) or both] and metabolic control (HbA1c) as well as body adiposity (BMI-SDS) over-time in a cohort of children and adolescents with type 1 diabetes (T1D), that have never used these technologies before. Subjects and methods 4,643 T1D patients (2-18 years, T1D ≥1year, without celiac disease, no CSII and/or CGM before 2016) participating in the SWEET prospective multicenter diabetes registry, were enrolled. Data were collected at two points (2016;2019). Metabolic control was assessed by glycated hemoglobin (HbA1c) and body adiposity by BMI-SDS (WHO). Patients were categorized by treatment modality [multiple daily injections (MDI) or CSII] and the use or not of CGM. Linear regression models, adjusted for age, gender, duration of diabetes and region, were applied to assess differences in HbA1c and BMI-SDS among patient groups. Results The proportion of patients using MDI with CGM and CSII with CGM significantly increased from 2016 to 2019 (7.2% to 25.7%, 7.8% to 27.8% respectively; p Conclusions Switching from MDI to CSII is significantly associated with improvement in glycemic control but increased BMI-SDS over-time. Diabetes technology may improve glucose control in youths with T1D although further strategies to prevent excess fat accumulation are needed. This article is protected by copyright. All rights reserved. |
| تدمد: | 1399-5448 1399-543X |
| DOI: | 10.1111/pedi.13274 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::6ad56d66fc019263ea0f3e74d2cff9d2 https://doi.org/10.1111/pedi.13274 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi...........6ad56d66fc019263ea0f3e74d2cff9d2 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13995448 1399543X |
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| DOI: | 10.1111/pedi.13274 |