Health Assessment of Polycyclic Aromatic Hydrocarbon Mixtures: Current Practices and Future Directions

التفاصيل البيبلوغرافية
العنوان: Health Assessment of Polycyclic Aromatic Hydrocarbon Mixtures: Current Practices and Future Directions
المؤلفون: S. H. Rieth, G. L. Foureman, D. L. Murphy, R. Hertzberg, L. Flowers, V. J. Cogliano, E. L. Hofmann, R. S. Schoeny, S. Nesnow
المصدر: Polycyclic Aromatic Compounds. 22:811-821
بيانات النشر: Informa UK Limited, 2002.
سنة النشر: 2002
مصطلحات موضوعية: Chronic exposure, chemistry.chemical_classification, Coke oven, Diesel exhaust, Polymers and Plastics, Chemistry, Organic Chemistry, Polycyclic aromatic hydrocarbon, complex mixtures, Human health, Health assessment, Environmental chemistry, Environmental health, Materials Chemistry, Risk assessment
الوصف: The U.S. EPA's Integrated Risk Information System (IRIS) program has initiated a health assessment for polycyclic aromatic hydrocarbon (PAH) mixtures. The IRIS program develops EPA consensus scientific positions on potential human health effects from chronic exposure to chemicals. Currently, the IRIS database contains health assessments for the toxic effects of exposure to coke oven emissions, creosote, diesel emissions, and 15 individual PAH compounds. As a whole, these assessments do not consider issues related to the environmental occurrence of PAH compounds as complex mixtures. Risk assessment of PAH mixtures has been hindered by a lack of information on the composition and toxicity of specific mixtures, the components that contribute most to toxicity, and the interactions and differences in mode of action between components. The state-of-the-science has advanced considerably in the past decade and will play a key role in the development of the health assessment. Consideration of these issues led to a...
تدمد: 1563-5333
1040-6638
DOI: 10.1080/10406630290103960
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5ff410b321efa15a94452da3a1951b27
https://doi.org/10.1080/10406630290103960
رقم الانضمام: edsair.doi...........5ff410b321efa15a94452da3a1951b27
قاعدة البيانات: OpenAIRE
الوصف
تدمد:15635333
10406638
DOI:10.1080/10406630290103960