Seeded growth of hydroxyapatite in simulated body fluid
| العنوان: | Seeded growth of hydroxyapatite in simulated body fluid |
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| المؤلفون: | N. Spanos, Petros G. Koutsoukos, Dimitra G. Kanellopoulou, D. Y. Misirlis |
| المصدر: | Journal of Materials Science. 41:1805-1812 |
| بيانات النشر: | Springer Science and Business Media LLC, 2006. |
| سنة النشر: | 2006 |
| مصطلحات موضوعية: | Surface diffusion, Supersaturation, Materials science, Mechanical Engineering, Simulated body fluid, Kinetics, Inorganic chemistry, chemistry.chemical_element, Crystal growth, Calcium, chemistry, Mechanics of Materials, General Materials Science, Seed crystal, Biomineralization |
| الوصف: | The precipitation of calcium phosphates was investigated, in simulated body fluid (SBF), pH 7.40 and 37°C. The kinetics of the mineral phase forming in the SBF was measured using the constant supersaturation method. The approach provides a detailed investigation in the processes taking place in the SBF which is widely used for the study of biomineralization. The pH adjustment was done by a pH-stat instead of Tris-Buffer [Tris (hydroxymethyl) Aminomethane] to avoid the presence of organic soluble compounds. The stability of SBF was investigated and the stable supersaturated solutions were seeded. The technique of seeded precipitation was employed for the achievement of accurate and reproducible kinetics measurements. The crystal growth experiments in which SBF solutions of variable supersaturations were seeded with hydroxyapatite [Ca5(PO4)3OH, HAP] crystals showed that the precipitation of calcium phosphates took place exclusively on specific active sites provided on the surface of the synthetic seed crystals. The crystal growth mechanism showed that the process was controlled by surface diffusion. The phase formed was HAP in the lattice of which CO32− and Mg2+ ions were incorporated. SBF was the source of these ions. Moreover it was found that the less stable calcium phosphate dihydrate (CaHPO4·2H2O, DCPD) may form as a transient phase hydrolyzing rapidly into the more stable HAP. Morphological examination of the carbonated apatites formed in the SBF showed appreciable aggregation. |
| تدمد: | 1573-4803 0022-2461 |
| DOI: | 10.1007/s10853-006-2952-9 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::57bfd3f27f2f7c19cb5d79854f670a44 https://doi.org/10.1007/s10853-006-2952-9 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi...........57bfd3f27f2f7c19cb5d79854f670a44 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15734803 00222461 |
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| DOI: | 10.1007/s10853-006-2952-9 |