Background: The need for reliable respiratory monitoring has increased in recent years with the frequent use of opioids for perioperative pain management as well as a high prevalence of patients suffering from respiratory comorbidities. Objective: Motivated by the success of acoustical color spectrographic techniques in other knowledge domains, we sought to build proof-of-concept systems for the computer-based color spectrographic analysis of respiratory sounds, recorded from various sites. Methods: We used a USB miniature electret microphone and a Windows-based color spectrographic analysis package to obtain color spectrograms for breath sound recordings from the neck, from an oxygen mask, from the ear canal, and from a leak-free microphone pneumatically connected to the cuff of a laryngeal mask airway. Results: Potentially useful color spectrographic displays were obtained from all four recording sites, although the spectrograms obtained varied in their characteristics. It was also found that obtaining high-quality color spectrograms requires attention to a number of technical details. Conclusion: Color spectrographic analysis of respiratory sounds is a promising future technology for respiratory monitoring.