Clinical Outcomes of Drug-Eluting Balloon for In-Stent Restenosis Based on the Number of Metallic Layers
| العنوان: | Clinical Outcomes of Drug-Eluting Balloon for In-Stent Restenosis Based on the Number of Metallic Layers |
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| المؤلفون: | Takeo Horikoshi, Tatsuya Amano, Toru Naganuma, Miho Tada, Yusuke Watanabe, Satoko Tahara, Hiroyoshi Kawamoto, Tomohiko Sato, Koji Hozawa, Satoru Mitomo, Toru Yoshizaki, Takayuki Warisawa, Hisaaki Ishiguro, Yusuke Fujino, Naoyuki Kurita, Akihiro Nakajima, Sunao Nakamura, Hiroto Yabushita, Hirokazu Onishi, Shotarou Nakamura |
| المصدر: | Circulation: Cardiovascular Interventions. 11 |
| بيانات النشر: | Ovid Technologies (Wolters Kluwer Health), 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | medicine.medical_specialty, business.industry, medicine.medical_treatment, Percutaneous coronary intervention, 030204 cardiovascular system & hematology, medicine.disease, Balloon, Thrombosis, 03 medical and health sciences, 0302 clinical medicine, Restenosis, Internal medicine, medicine, Cardiology, cardiovascular diseases, 030212 general & internal medicine, Myocardial infarction, In stent restenosis, Cardiology and Cardiovascular Medicine, Drug eluting balloon, business |
| الوصف: | Background: This study assesses clinical outcomes after drug-eluting balloon treatment for recurrent in-stent restenosis lesions based on the number of metallic layers. Methods and Results: We enrolled 304 consecutive patients (333 lesions) treated with percutaneous coronary intervention using drug-eluting balloon for in-stent restenosis lesions between March 2014 and June 2015. Per the number of stent layers previously implanted to the lesion, the patients were categorized into 3 groups, 1 stent layer (1L), 166 patients; 2 stent layers (2L), 87 patients; and ≥3 stent layers (≥3L), 51 patients. The end points were major adverse cardiovascular events (MACE), including cardiac death, target lesion revascularization, myocardial infarction, and definite or probable stent thrombosis. No significant differences were observed in patients’ baseline characteristics among the groups. The 1-year MACE and target lesion revascularization rates were significantly higher in the ≥3L group than those in the 1L and 2L groups (MACE: 1L, 16.9%; 2L, 16.1%; and ≥3L, 43.1%, P P P P =0.02]) were independent predictors for MACE. No significant differences were observed in the occurrence of cardiac death among the groups ( P =0.34). Conclusions: Seemingly, drug-eluting balloon is less effective for ≥3L in-stent restenosis lesions. Hemodialysis and in-stent restenosis with the number of metallic layers are independent predictors for MACE. |
| تدمد: | 1941-7632 1941-7640 |
| DOI: | 10.1161/circinterventions.117.005935 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::530e5cc0af767534d8d8aa959eb57b7f https://doi.org/10.1161/circinterventions.117.005935 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi...........530e5cc0af767534d8d8aa959eb57b7f |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19417632 19417640 |
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| DOI: | 10.1161/circinterventions.117.005935 |