Differential scanning calorimetric examination of the human hyaline cartilage of the femoral head after femoral neck fracture

التفاصيل البيبلوغرافية
العنوان: Differential scanning calorimetric examination of the human hyaline cartilage of the femoral head after femoral neck fracture
المؤلفون: L. Vámhidy, I. Naumov, Balázs Patczai, N. Wiegand, Dénes Lőrinczy
المصدر: Journal of Thermal Analysis and Calorimetry. 108:59-65
بيانات النشر: Springer Science and Business Media LLC, 2011.
سنة النشر: 2011
مصطلحات موضوعية: Materials science, Hyaline cartilage, business.industry, Cartilage, Avascular necrosis, Condensed Matter Physics, medicine.disease, Femoral Neck Fractures, Femoral head, medicine.anatomical_structure, Vascularity, medicine, Fracture (geology), Physical and Theoretical Chemistry, medicine.symptom, Nuclear medicine, business, Femoral neck
الوصف: The femoral neck fracture continues to be unsolved fractures and the guidelines for management are still evolving. The primary complications arising from femoral neck fractures are non-union and avascular necrosis. The various methods currently available for predicting the vascularity of the head at the time of fracture are not sufficiently quantitative to be used on a routine clinical basis. The hypothesis was that after the femoral neck fracture there are clear pathological abnormalities in the cartilage of the femoral head, which could be monitored besides the classical methods by differential scanning calorimetry. The thermal denaturation of human samples was monitored by a SETARAM Micro DSC-II calorimeter. All the experiments were performed between 0 and 100 °C. The heating rate was 0.3 K/min. DSC scans clearly demonstrated significant differences between the control and different stages avascular samples (control, fresh fractures: T m = 68.2 °C, ΔH cal = 2.87 J/g, avascular necrosis: T m = 70.7 °C, ΔH cal = 3.61 J/g,). These observations could be explained with the structural alterations caused by the biochemical processes during the degeneration of the cartilage due to avascular femoral head necrosis. With the investigations the authors could demonstrate that DSC is a useful and well-applicable method for the investigation of hyaline cartilage of the fractured human femoral head. It was confirmed significances between the changes of calorimetric results and the elapsed time from the primary femoral neck fracture.
تدمد: 1572-8943
1388-6150
DOI: 10.1007/s10973-011-1532-7
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::50484edf876c96df9358e9199333fa84
https://doi.org/10.1007/s10973-011-1532-7
Rights: CLOSED
رقم الانضمام: edsair.doi...........50484edf876c96df9358e9199333fa84
قاعدة البيانات: OpenAIRE
الوصف
تدمد:15728943
13886150
DOI:10.1007/s10973-011-1532-7