Principal-coordinate analysis suggests that Vachellia × cedilloi is of hybrid origin. Probable parents are V. cornigera and V. globulifera. This putative hybrid shows a relationship to V. cornigera with a much smaller, but similar, short spike-like inflorescence with a cone-shaped receptacle and leaves with relatively few pairs of pinnae. In contrast, the columnar to narrow volcano-shaped rachis glands, along with narrow stipular spines, indicate a relationship to V. globulifera.