Professional adaptation of specialists takes place not only after the stages of employment, but also with changes in technology, regulations, production culture. At the same time, forecasting the level of staff resistance to changes will reduce the additional costs, build an adequate system of professional development and prepare personnel for changes. This publication examines the example of determining the degree of resistance of personnel to changes in the requirements of the international standard ISO 9001. The calculation of the resistance level is based on the comparison of the requirements of the international standard ISO 9001 and the current quality management system. An analysis of the perception of the quality management system by employees was based on the questionnaire survey of the heads of structural divisions. Further, the results of the questionnaire were compared with the semantic model of the international standard ISO 9001. The level of inconsistency indicates the possible resistance of personnel to the introduction of new requirements.