Aim To clarify the diagnosis and treatment of epilepsy with higher brain dysfunction (E-HBD). Methods Using neuropsychological testing we identified three cases. Results All three cases showed persistent aphasia, amnesia or attention deficits – possibly connected with epilepsy – and were treated with anti-epileptic drugs (AED). Although the AED proved effective, there were no findings of non-convulsive status epileptics. Conclusion The etiology of E-HBD is unclear, but treatment with AED alleviated the higher brain function deficits in our three patients.