Accepting the challenge launched by this issue of Ardeth, this commentary is conceived as a short interview with three innovative architectural practices involved in the last Shenzhen Bienniale, namely: Sara Dean (VUCA), Seiche and Nicholas Korody (Adjustments Agency). By means of four questions, the three practices quickly portray how the wider issue of loss influences their way they work and the way in which a contemporary architectural practice is supposed to work nowadays. At stake are reasons behind their approach to architecture proving the deliberately overcoming of disciplinary borders as well as more general remarks about their acknowledgement of loss as an event involved in the process of legitimation of their practices.