ChemInform Abstract: Total Synthesis and the Confirmation of the Revised Structures of Botcinins A and B
| العنوان: | ChemInform Abstract: Total Synthesis and the Confirmation of the Revised Structures of Botcinins A and B |
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| المؤلفون: | Hiroki Fukui, Keisuke Tsuji, Isamu Shiina, Yuma Umezaki |
| المصدر: | ChemInform. 40 |
| بيانات النشر: | Wiley, 2009. |
| سنة النشر: | 2009 |
| مصطلحات موضوعية: | chemistry.chemical_compound, chemistry, Stereochemistry, Botcinin E, Natural compound, Botcineric acid, Total synthesis, Stereoselectivity, General Medicine, Tetrahydropyran, Botcinic acid |
| الوصف: | The stereoselective total syntheses of botcinins A (1) and B (2), and homobotcinin E (4), a homologue of botcinin E (3), have been achieved starting from a polyoxygenated tetrahydropyran intermediate 15 via formation of botcinic acid (12) and botcineric acid (13). Through the total syntheses, three actual relationships are revealed, that is, (i) the structure of botcinin A (1) is identical with the revised structure of the natural compound, which was formerly assumed to be 3-O-acetyl-2-epibotcinolide (5), (ii) the structure of botcinin B (2) is identical with the revised structure of the natural compound, which was supposed to be 3-O-acetyl-2-epihomobotcinolide (6), and (iii) the structure of the natural compound formerly assumed to be 2-epihomobotcinolide (8) must be revised to that of homobotcinin E (4). |
| تدمد: | 1522-2667 0931-7597 |
| DOI: | 10.1002/chin.200940210 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::47925f073ad59febae2942ef2013d57d https://doi.org/10.1002/chin.200940210 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi...........47925f073ad59febae2942ef2013d57d |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15222667 09317597 |
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| DOI: | 10.1002/chin.200940210 |