Families experience various kinds of problems and problems in caring for family members whose families experience various obstacles in treating a patient with mental disorders. One condition that is felt is anxiety. Anxiety is related to ignorance regarding the patient's condition; earn a living; demands to divide time. The role of the family becomes very important because the patient lives in the middle of the family. Families need knowledge in managing patients both when treated at the hospital and when returning home. The purpose of this study was to determine the effect of family psychoeducation (FPE) therapy on family anxiety in treating a patient with mental disorders. The design used a quasi-experiment with the pre-test and post-test with control group methods. The sample was 100 respondents (50 experimental groups and 50 control groups). The results of the study showed a significant effect of FPE on family anxiety with a p-value of 0.00 (p