Graft survival and clinical outcomes of Descemet membrane endothelial keratoplasty: long-term results
| العنوان: | Graft survival and clinical outcomes of Descemet membrane endothelial keratoplasty: long-term results |
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| المؤلفون: | Gülay Yalçınkaya, Yusuf Yildirim, Ahmet Kirgiz, Alper Agca, Selim Genç, Semih Çakmak, Nilay Kandemir Besek, Senay Asik Nacaroglu, Burcin Kepez Yildiz |
| المصدر: | International Ophthalmology. 42:269-279 |
| بيانات النشر: | Springer Science and Business Media LLC, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | medicine.medical_specialty, Visual acuity, genetic structures, Descemet membrane, business.industry, medicine.medical_treatment, eye diseases, Confidence interval, Log-rank test, Transplantation, Ophthalmology, Bullous keratopathy, medicine, Graft survival, sense organs, medicine.symptom, business, Corneal transplantation |
| الوصف: | Purpose The aim is to report long-term graft survival rates and clinical outcomes of Descemet membrane endothelial keratoplasty (DMEK). Methods In this study 150 eyes that underwent DMEK whether for Fuchs endothelial corneal dystrophy (FECD) or for bullous keratopathy (BK) surveilled for 7 years at 6 time points to evaluate graft survival rates and clinical outcomes of post-corneal transplantation. Results Overall, the estimated survival probability of 95% confidence interval at 7 years of post-DMEK was 0.58 (0.72-0.77), and the survival probabilities of eyes operated for FECD (0.53) were higher than eyes operated for BK (0.42) (log rank 26.87, [p = 0.197]). Post-transplant eyes with FECD achieved better visual acuity levels than eyes with BK (p = 0.006). Primary graft failure occurred in 11.3% eyes. Secondary graft failure rate was 9.3%, and allograft rejection rate was 4.7%. Conclusion Although DMEK is effective and safe in long term, visual results and graft survival rates are better in cases with FECD. |
| تدمد: | 1573-2630 0165-5701 |
| DOI: | 10.1007/s10792-021-02078-4 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::44667b3445758367916438483c1e693a https://doi.org/10.1007/s10792-021-02078-4 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi...........44667b3445758367916438483c1e693a |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15732630 01655701 |
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| DOI: | 10.1007/s10792-021-02078-4 |