BACKGROUND Left bundle branch area pacing (LBBAP) has emerged as a promising pacing modality for physiologic pacing. Atrioventricular heart block is a common complication after a valvular intervention but there are limited data on the performance of LBBAP in this population. The aim of this study is to evaluate the safety and feasibility of LBBAP in patients with valvular interventions. METHODS AND RESULTS Seventy-nine patients were included in this study. All patients underwent surgical or percutaneous valvular interventions. LBBAP was attempted in all patients. Implant success rates, peri- and post procedure ECG, pacing parameters, and complications were assessed at implant, and during follow-up. LBBAP implantation was successful in 75/79 (95 %) patients. Mean age was 70.9 ± 13.8 years and 65 % patients were male. Prior interventions included TAVR (25), SAVR (34), combined surgical AVR plus MVR (6), MVR (8), TVR (1), and PVR (1). Average LVEF was 52.6 ± 10.7 %. Total procedure duration was 74.3 ± 37.3 min and fluoroscopic duration was 9.8 ± 7.0 min. Pacing parameters were stable during follow up period of 8.1 ± 4.9 months. Pacing QRS duration was significantly narrower than baseline QRS duration (130.5 ± 30.6 ms vs. 113.9 ± 14.0 ms, p CONCLUSION LBBAP is feasible and safe pacing modality in patients with prior interventions for valvular heart disease.