Tibial Bone Quality in Former Bariatric Surgery Patients with Osteoarthritis
| العنوان: | Tibial Bone Quality in Former Bariatric Surgery Patients with Osteoarthritis |
|---|---|
| المؤلفون: | Emily Leary, Dana L. Duren, Richard J. Sherwood, Breanne S Baker, Chantelle C. Bozynski, James L. Cook, James A. Keeney |
| المصدر: | Obesity Surgery. 31:5322-5329 |
| بيانات النشر: | Springer Science and Business Media LLC, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | medicine.medical_specialty, Nutrition and Dietetics, business.industry, Osteoid, Endocrinology, Diabetes and Metabolism, Disease progression, Total knee arthroplasty, Osteoarthritis, medicine.disease, Bone resorption, Surgery, Implant fixation, medicine.anatomical_structure, Osteoclast, Medicine, Tibial bone, business |
| الوصف: | Downstream effects of bariatric weight-loss surgery have been associated with bone resorption, potentially jeopardizing total knee arthroplasty (TKA) implant fixation/ingrowth. This case–control study sought to determine if TKA patients with history of bariatric surgery exhibit altered microanatomy of subchondral bone quality in the tibial plateau compared to controls. With IRB approval, 41 bone samples were evaluated from 12 former bariatric surgery patients and 10 sex-, age-, weight-, height-, and BMI-matched controls. Patient-Reported Outcomes Measurement Information System (PROMIS) surveys were completed prior to TKA. Tibial plateau osteochondral tissues were recovered during the TKA procedure, and samples from the medial and lateral plateaus were dissected into 1 × 2 cm sections, scanned using microcomputed tomography (µCT), and plastic-embedded for histologic sectioning/staining of undecalcified bone. Paired t tests with Bonferroni correction were performed to assess group differences. Female bariatric surgery patients had reduced osteoid/total area and greater osteoclast number asymmetry than female controls (p |
| تدمد: | 1708-0428 0960-8923 |
| DOI: | 10.1007/s11695-021-05727-w |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::3b5305a9b5880737d6d471bd20fc1133 https://doi.org/10.1007/s11695-021-05727-w |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi...........3b5305a9b5880737d6d471bd20fc1133 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17080428 09608923 |
|---|---|
| DOI: | 10.1007/s11695-021-05727-w |