ChemInform Abstract: Zn-Catalyzed Enantio- and Diastereoselective Formal [4 + 2] Cycloaddition Involving Two Electron-Deficient Partners: Asymmetric Synthesis of Piperidines from 1-Azadienes and Nitro-Alkenes
التفاصيل البيبلوغرافية
العنوان:
ChemInform Abstract: Zn-Catalyzed Enantio- and Diastereoselective Formal [4 + 2] Cycloaddition Involving Two Electron-Deficient Partners: Asymmetric Synthesis of Piperidines from 1-Azadienes and Nitro-Alkenes
The novel bisoxazoline diphenylamine ligand (OXA) provides high reactivity and enantioselectivity in the title process, which is proposed to proceed in a stepwise manner via Michael-type addition of the imine to the nitroalkane followed by cyclization.