We examined the gender dependence of the relationships between sensory and affective pain and pain catastrophizing. Study participants were 170 people who were receiving treatment for chronic pain at a university pain clinic in Daegu, Republic of Korea. For men, higher levels of sensory pain were associated with greater pain catastrophizing at low and average levels of affective pain, but not at a high level of affective pain. For women, higher levels of affective pain were associated with greater pain catastrophizing, regardless of the degree of sensory pain. These results suggest that sensory pain, affective pain, and their combination may have gender-dependent effects on pain catastrophizing in people who are experiencing chronic pain. Most importantly, affective pain appears to play a major role in pain catastrophizing, regardless of gender and, for men, the role of sensory pain in pain catastrophizing requires consideration.