Method for Living Cell Mechanical Properties Evaluation from Force-Indentation Curves
| العنوان: | Method for Living Cell Mechanical Properties Evaluation from Force-Indentation Curves |
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| المؤلفون: | Raimundas Vilkoncius, Juste Rozene, Oleksii Balitskyi, Andrius Dzedzickis, Almira Ramanaviciene, Antanas Zinovicius, Vytautas Bučinskas, Arunas Ramanavicius, Inga Morkvenaite-Vilkonciene |
| المصدر: | Advances in Intelligent Systems and Computing ISBN: 9783030132729 AUTOMATION |
| بيانات النشر: | Springer International Publishing, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Work (thermodynamics), Materials science, Atomic force microscopy, 0206 medical engineering, Modulus, 02 engineering and technology, Living cell, Elasticity (physics), 021001 nanoscience & nanotechnology, 020601 biomedical engineering, Finite element method, Membrane, Indentation, Composite material, 0210 nano-technology |
| الوصف: | Living cells mechanical properties establishment from Atomic force microscopy (AFM) force-separation curves is a challenge because the calculated Young’s modulus depends on the applied mathematical model. The more reliable results can be obtained using finite element models. In this work, yeast cells with different mechanical properties were measured by AFM. To change cells mechanical properties, yeasts were immersed in 9, 10-phenanthrenequinone, which changed cells’ membranes elasticity. 3D finite element model of the whole cell was created to calculate reacting force when AFM tip indents the cell in the same way as in the real experiment. It was found that our model is capable to draw the information about cells mechanical properties and visco-elastic behavior of cells membranes. |
| ردمك: | 978-3-030-13272-9 |
| DOI: | 10.1007/978-3-030-13273-6_61 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::15128b2264a294fdb3b83f2743f36198 https://doi.org/10.1007/978-3-030-13273-6_61 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi...........15128b2264a294fdb3b83f2743f36198 |
| قاعدة البيانات: | OpenAIRE |
| ردمك: | 9783030132729 |
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| DOI: | 10.1007/978-3-030-13273-6_61 |