X-ray diffraction study of the complex of the enzyme SAICAR synthase with the reaction product
| العنوان: | X-ray diffraction study of the complex of the enzyme SAICAR synthase with the reaction product |
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| المؤلفون: | Svetlana V. Antonyuk, V. R. Melik-Adamyan, A. I. Grebenko, Victor S. Lamzin, Vladimir M. Levdikov, D.V. Urusova |
| المصدر: | Crystallography Reports. 51:824-827 |
| بيانات النشر: | Pleiades Publishing Ltd, 2006. |
| سنة النشر: | 2006 |
| مصطلحات موضوعية: | chemistry.chemical_classification, DNA ligase, ATP synthase, biology, Stereochemistry, Substrate (chemistry), Active site, General Chemistry, Condensed Matter Physics, Amino acid, chemistry.chemical_compound, Crystallography, Enzyme, chemistry, Succinic acid, X-ray crystallography, biology.protein, General Materials Science |
| الوصف: | The three-dimensional structure of the complex of the enzyme SAICAR synthase with the product of the enzymatic reaction, SAICAR, was solved and refined by methods of protein crystallography. The SAICAR-binding site in the active site of the enzyme was found. The amino-acid residues providing the binding of the reaction product with the protein were revealed. These residues were compared with those involved in the substrate binding in the complex with AICAR and succinic acid studied earlier. |
| تدمد: | 1562-689X 1063-7745 |
| DOI: | 10.1134/s1063774506050129 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::0f9752dc2cd64d69200d44d4a32d1949 https://doi.org/10.1134/s1063774506050129 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi...........0f9752dc2cd64d69200d44d4a32d1949 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1562689X 10637745 |
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| DOI: | 10.1134/s1063774506050129 |