Background Group B streptococcus is a frequent cause of sepsis and neonatal death The objective of the present study is to characterize the behavior of Group B streptococcal meningitis in Cuban infants Methods A years lasting retrospective observational study of cases of Group B streptococcal meningitis was carried out January st December st Risk was estimated annually by age and gender as well as case fatality rate and the association of delay in medical consultation and hospitalization with death Results Overall incidence was live births mortality rate live births and case fatality rate of Sex ratio reached Infants younger than one month represented the largest proportion of cases accounting the majority of deceased with case fatality rate of Early onset of disease occurred in cases late onset in cases and presented young infant disease No deaths reported among cases with early onset of disease but in late onset and infant disease occurred and nine young infant disease respectively Around a quarter of cases share dormitories with ge individuals The overall mean time for consultation and hospital admittance was lower than hours Weak RR CI p lt in cases with late onset of disease or no association of delay in medical consultation and hospital admittance with death was demonstrated Conclusion GBS meningitis still persists as an important and preventable cause of meningitis and neonatal and infant mortality in Cuba Monitoring and detection of changes in the behavior of these infections has been demonstrated necessary and useful for prevention and control of these life threatening infections Background Group B streptococcus is a frequent cause of sepsis and neonatal death The objective of the present study is to characterize the behavior of Group B streptococcal meningitis in Cuban infants Methods A years lasting retrospective observational study of cases of Group B streptococcal meningitis was carried out January st December st Risk was estimated annually by age and gender as well as case fatality rate and the association of delay in medical consultation and hospitalization with death Results Overall incidence was live births mortality rate live births and case fatality rate of Sex ratio reached Infants younger than one month represented the largest proportion of cases accounting the majority of deceased with case fatality rate of Early onset of disease occurred in cases late onset in cases and presented young infant disease No deaths reported among cases with early onset of disease but in late onset and infant disease occurred and nine young infant disease respectively Around a quarter of cases share dormitories with ge individuals The overall mean time for consultation and hospital admittance was lower than hours Weak RR CI p lt in cases with late onset of disease or no association of delay in medical consultation and hospital admittance with death was demonstrated Conclusion GBS meningitis still persists as an important and preventable cause of meningitis and neonatal and infant mortality in Cuba Monitoring and detection of changes in the behavior of these infections has been demonstrated necessary and useful for prevention and control of these life threatening infections