Associations of Imaging Markers of Small Vessel Disease and 'Brain Frailty' with Clinical Outcome in Patients with Acute Lacunar Stroke: A Secondary Analysis of the Efficacy of Nitric Oxide in Stroke (ENOS) Trial
التفاصيل البيبلوغرافية
العنوان:
Associations of Imaging Markers of Small Vessel Disease and 'Brain Frailty' with Clinical Outcome in Patients with Acute Lacunar Stroke: A Secondary Analysis of the Efficacy of Nitric Oxide in Stroke (ENOS) Trial
Background: Cerebral small vessel disease (SVD) is a common cause of lacunar stroke, cognitive impairment and dementia. We assessed the association of baseline imaging markers of SVD and 'brain frailty' with functional and cognitive outcomes after acute stroke, including lacunar stroke, in the Efficacy of Nitric Oxide in Stroke (ENOS) trial. Methods: ENOS randomised 4011 patients with acute stroke (