This research reports a selective detecting and focusing approach for fatigue cracks through use of decomposition of the time reversal operator (DORT) in combination with nonlinear Lamb waves. In the proposed approach, the time reversal operator (TRO) is only decomposed at the second-harmonic frequency, which has been widely utilized in recent years to evaluate micro-damage, rather than the fundamental frequency in the traditional DORT method. Further, an imaging algorithm based on the total focus method is introduced to locate nonlinear scatterers. The proposed approach is experimentally investigated to locate two fatigue cracks with different fatigue cycles in an aluminum plate with a set of surface bounded piezoelectric (PZT) transducers. The results show that the significant eigenvalues are related to the fatigue cycles of fatigue cracks when the TRO is decomposed at the second-harmonic frequency, and the number of significant eigenvalues is exactly equal to the number of fatigue cracks. The two fatigue cracks are selectively located accurately and are also distinguished from linear scatterer by use of the proposed method.