Relative exposure to controller therapy and asthma exacerbations: a validation study in community pharmacies

التفاصيل البيبلوغرافية
العنوان: Relative exposure to controller therapy and asthma exacerbations: a validation study in community pharmacies
المؤلفون: L. Laforest, Geneviève Chamba, Gilles Devouassoux, Gérard Chatté, Manon Belhassen, Idlir Licaj, Eric Van Ganse
المصدر: Pharmacoepidemiology and Drug Safety. 23:958-964
بيانات النشر: Wiley, 2014.
سنة النشر: 2014
مصطلحات موضوعية: Drug, medicine.medical_specialty, Community pharmacies, Epidemiology, business.industry, media_common.quotation_subject, Pharmacy, Inhaled corticosteroids, Pharmacoepidemiology, medicine.disease, 3. Good health, 03 medical and health sciences, 0302 clinical medicine, 030228 respiratory system, Internal medicine, Physical therapy, medicine, Pharmacology (medical), 030212 general & internal medicine, Medical prescription, business, Disease burden, media_common, Asthma
الوصف: Purpose “Controllers-to-total asthma drug” ratios computed from claims data identify asthmatics at risk of exacerbations. Direct link of ratios to data obtained from patients, such as control and recent outcomes, would facilitate their interpretation. We studied the relationship between R1 ratio (inhaled corticosteroids (ICS)/total anti-asthma drug ratio) and the Asthma Control Test. Comparisons were also conducted for secondary outcomes (asthma-related hospital contacts, monthly medical contacts, use of oral corticosteroids, and perception of disease burden). Results with R1 ratio were compared with those obtained with a second ratio, “ICS-plus-leukotriene receptor antagonist/total asthma drug” (R2 = ICS + leukotriene receptor antagonist/total anti-asthma drugs). Methods A survey was conducted in community pharmacies. Patients visiting with a prescription of anti-asthma drug and ≥12 months of drug dispensing recorded in the pharmacy were consecutively recruited. Dispensing data were linked to patient-reported outcomes. Asthma control and secondary outcomes were compared for both ratios between low-controller-ratio (R
تدمد: 1053-8569
DOI: 10.1002/pds.3668
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::00dc4904ed55eeeaf3646a0c3600ecb1
https://doi.org/10.1002/pds.3668
Rights: CLOSED
رقم الانضمام: edsair.doi...........00dc4904ed55eeeaf3646a0c3600ecb1
قاعدة البيانات: OpenAIRE
الوصف
تدمد:10538569
DOI:10.1002/pds.3668