Antiulcer activity of ethanolic extract of Encholirium spectabile Mart. ex Schult & Schult f. (Bromeliaceae) in rodents
| العنوان: | Antiulcer activity of ethanolic extract of Encholirium spectabile Mart. ex Schult & Schult f. (Bromeliaceae) in rodents |
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| المؤلفون: | Moraes Carvalho, Katharinne I., Fernandes, Helio B., Frota Machado, Flavia D., Oliveira, Irisdalva S., Oliveira, Francisco A., Nunes, Paulo Humberto M., Lima, Julianeli T., Jackson Almeida, Meneses Oliveira, Rita C. |
| المصدر: | Biological Research, Vol 43, Iss 4, Pp 459-465 (2010) Biological Research, Volume: 43, Issue: 4, Pages: 459-465, Published: 2010 ResearcherID |
| بيانات النشر: | BMC, 2010. |
| سنة النشر: | 2010 |
| مصطلحات موضوعية: | Encholirium spectabile, Bromeliaceae, antioxidant, lcsh:Biology (General), antiulcer activity, lcsh:QH301-705.5 |
| الوصف: | This study evaluated the antiulcer activity of an ethanolic extract of Encholirium spectabile (ES-EtOH) by using different standard experimental models of induced acute gastric ulceration. ES-EtOH (100 mg/kg p.o) protected the gastric mucosa against ulceration that was induced by absolute ethanol (53%), ethanol/HCl (75 %), ibuprofen (52 %) and ischemia/reperfusion (43 %). It also restored catalase activity and non-protein sulfhydryl group concentration in the gastric wall of mice that had been treated with ethanol. The pre-treatment of mice with N-nitro-L-arginine (70 mg/kg i.p.) abolished the protective activity of ES-EtOH, which indicates that prostaglandins, antioxidant compounds and nitric oxide synthase activity are involved in the gastroprotective activity of the extract. |
| وصف الملف: | text/html |
| اللغة: | English |
| تدمد: | 0717-6287 0716-9760 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::cbcf328e50dc0db0f0e80db4488475f1 http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602010000400011 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.dedup.wf.001..cbcf328e50dc0db0f0e80db4488475f1 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 07176287 07169760 |
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