The concept of Buon Vivere (Good Living) is a set of good practices and fundamental principles that inspire communities to create new foundations based on the values of equality, sustainability, responsible innovation, an ethical economy, and knowledge. These are the fundamental elements of a society capable of putting people and the relationships between genders, generations, and cultures at its center. The relationship economy is a social system where the behaviors, choices, decisions, and benefits of economic agents are highly dependent on the quality and quantity of their relationships. Therefore, a reflection on Buon Vivere as Relationship Economy must be carried out in multidisciplinary terms ranging from economics to psychology, from urban planning to health care, the challenges of a digital world, and research on development always maintaining a focus on issues of equity and the fundamental role of culture. The essays collected in this book examine the elements that currently prevent or foster Buon Vivere within individual fields. This book is a concrete tool, versatile for education and the promotion of awareness on the topic and its applications.