Factores de riesgo para infección urinaria por Escherichia coli BLEE positiva

التفاصيل البيبلوغرافية
العنوان: Factores de riesgo para infección urinaria por Escherichia coli BLEE positiva
المؤلفون: CARCAUSTO-HUAMANÍ, EDUARDO, RODRÍGUEZ-HURTADO, DIANA
المصدر: Acta Medica Colombiana, Volume: 47, Issue: 3, Pages: 1-6, Published: 06 NOV 2022
Acta Medica Colombiana, Volume: 47, Issue: 2, Pages: 12-7, Published: 04 JAN 2023
بيانات النشر: Asociacion Colombiana de Medicina Interna, 2022.
سنة النشر: 2022
مصطلحات موضوعية: caso-control, infección urinaria, extended-spectrum beta-lactamase (ESBL), urinary tract infection, case-control, beta lactamasa de espectro extendido (BLEE)
الوصف: Objective: to determine the association of prior antibiotic use, prior hospitalizations, prior urinary tract infections, age, sex and comorbidities in adult patients hospitalized with urinary tract infections caused by extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli. Materials and methods: a case-control study carried out in the hospital setting of private clinics in Lima. Thirty cases and 30 controls were included, with cases defined as hospitalized patients with an ESBL-producing E. coli urinary tract infection diagnosed by urine culture, and controls defined as hospitalized patients without ESBL-producing E. coli infection. Data were taken from incident cases. A bivariate analysis was performed followed by multivariate logistic regression using the significant variables from the bivariate analysis. Results: the associated factors were: prior antibiotic use OR: 261 (22.5-11,017.4), prior hospital ization OR: 4.6 (1.39-16.1), and prior urinary tract infection OR: 36 (6.9-227.2). After adjusting for potential confounding factors using logistic regression, the main statistically significant associated factor was prior antibiotic use, OR: 97.7 (8.4-1,128.3, p
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