Periodical
Trichosporon asahiicausing subcutaneous mycoses in an immunocompetent patient: case report and a minireview
| العنوان: | Trichosporon asahiicausing subcutaneous mycoses in an immunocompetent patient: case report and a minireview |
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| المؤلفون: | Kruschewsky, Wdson Luis Lima, Massaroni-Peçanha, Pedro, Maifrede, Simone Bravim, Leite, Marcelo Santos, Pôssa, Tâmea Aparecida Linhares, Alberto-Lei, Felipe, Cayô, Rodrigo, Peçanha, Paulo Mendes, Gonçalves, Sarah Santos |
| المصدر: | Brazilian Journal of Microbiology; 20220101, Issue: Preprints p1-9, 9p |
| مستخلص: | Trichosporonspp. are a constituent of the normal flora of humans that can cause both superficial and invasive infections, mainly in immunocompromised and immunocompetent hosts, respectively. Herein, we a report of Trichosporon asahiicausing subcutaneous fungal infection (SFI) in an immunocompetent patient after carpal tunnel surgery. Although susceptible to fluconazole, the treatment of SFI failed even using high doses of this azole. The skin lesion improved following the administration of voriconazole. We conducted a literature minireview searching reports on SFI in immunocompetent patients to check for epidemiological, diagnostic, therapeutic, and outcome characteristics. A total of 32 cases were reported. Despite being uncommon, the clinical suspicion and early diagnosis of SFI in immunocompetent patients undergoing previous surgery are important. Our study indicated that the azoles are the most active antifungal agents against Trichosporonspp., except for fluconazole, and voriconazole can be considered the first therapeutic option. |
| قاعدة البيانات: | Supplemental Index |
Full Text Finder | تدمد: | 15178382 16784405 |
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| DOI: | 10.1007/s42770-022-00737-x |