Periodical
Planar, SPET and threedimensional immunoscintigraphy of suspected recurrent colorectal cancer using 111InB72.3 Oncoscint CROV Effect of administered activity
| العنوان: | Planar, SPET and threedimensional immunoscintigraphy of suspected recurrent colorectal cancer using 111InB72.3 Oncoscint CROV Effect of administered activity |
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| المؤلفون: | PERKINS, A. C., VINCENT, R. M., WASTIE, M. L., DENTON, G. W.L., AMAR, S., HARDCASTLE, J. D. |
| المصدر: | Nuclear Medicine Communications; December 1994, Vol. 15 Issue: 12 p981-990, 10p |
| مستخلص: | The monoclonal antibody conjugate 111InB72.3 was the first such antibodybased radiopharmaceutical for tumour detection to be granted a propriety product licence in Europe. However, the optimum activity of 111In for planar and SPET imaging is yet to be established. A baseline study of 20 patients with suspected recurrent colorectal cancer has been carried out to assess any effect of administered activity of radionuclide on image quality and tumour detection. Ten patients were administered 80 MBq 111InOncoscint and 10 patients a larger amount of activity, 150 MBq resulting in effective dose equivalents of 25 and 47 mSv, respectively. Planar, orthogonal SPET and 3D volumerendered SPET images were obtained and the image quality was assessed. The clinical results were compared with computed tomography CT and in selected patients magnetic resonance imaging MRI. |
| قاعدة البيانات: | Supplemental Index |
| تدمد: | 01433636 14735628 |
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