Periodical
Screening of selected plant extracts forin vitroinhibitory activity on Human Immunodeficiency Virus
| العنوان: | Screening of selected plant extracts forin vitroinhibitory activity on Human Immunodeficiency Virus |
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| المؤلفون: | Bedoya, L. M., Palomino, S. Sanchez, Abad, M. J., Bermejo, P., Alcami, J. |
| المصدر: | Phytotherapy Research; September 2002, Vol. 16 Issue: 6 p550-554, 5p |
| مستخلص: | As part of our screening of anti‐AIDS agents from natural sources, extracts of 15 medicinal plants widely used in the folk medicines of North America and Europe were evaluated in vitro. Most of the extracts tested were relatively nontoxic to human lymphocytic MT‐2 cells, but only the extracts of Hysopp officinalisand Dittrichia viscosaexhibited anti‐HIV activity in an in vitroMTT assay. The 50% hydroalcohol extract of Hysopp officinalisand the aqueous extract of Dittrichia viscosashowed inhibitory effects against HIV‐1 induced infections in MT‐2 cells at concentrations ranging from 50 to 100 μg/mL and 25 to 400 μg/mL, respectively. Both extracts showed no appreciable cytotoxicity at these concentrations. Copyright © 2002 John Wiley & Sons, Ltd. |
| قاعدة البيانات: | Supplemental Index |
| تدمد: | 0951418X 10991573 |
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| DOI: | 10.1002/ptr.992 |