Periodical
964-8 Oral Loading with Propafenone in Recent-Onset Atrial Fibrillation: A Controlled Evaluation on 240 Patients
| العنوان: | 964-8 Oral Loading with Propafenone in Recent-Onset Atrial Fibrillation: A Controlled Evaluation on 240 Patients |
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| المؤلفون: | Capucci, Alessandro, Boriani, Giuseppe, Luca Botto, G., Rubino, Ida, Falcone, Camillo, Casa, Stefano Della, Sanguinetti, Mario, Magnani, Bruno |
| المصدر: | Journal of the American College of Cardiology; February 1995, Vol. 25 Issue: 2, Number 2 Supplement 1 p219A-220A, 2p |
| مستخلص: | Aim of this placebo-controlled study was to assess efficacy and safety of an acute oral loading of propafenone (PFN) in converting recent-onset atrial fibrillation IAF) (≤7 days duration) to sinus rhythm (SR). Two hundred fourty hospitalised patients, NYHA class≤2, without signs or symptoms of heart failure or left ventricular dysfunction, after 2 hours of clinical observation were randomly allocated to treatment with PFN 1600 mg p.o. as single dose) or placebo (PLA). The patients were submitted to Holter monitoring and conversion to SR was evaluated at 3 and 8 hours.Results:PFN (n=119)PLA(n=121)SR≤3 hours54 (45%)22 (18%)*SR≤8 hours91 (76%)45 (37%)**P<0.001 |
| قاعدة البيانات: | Supplemental Index |
Full Text Finder | تدمد: | 07351097 15583597 |
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| DOI: | 10.1016/0735-1097(95)92371-B |