Periodical
Molecular cloning of a cDNA encoding human antihaemophilic factor
| العنوان: | Molecular cloning of a cDNA encoding human antihaemophilic factor |
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| المؤلفون: | Toole, John J., Knopf, John L., Wozney, John M., Sultzman, Lisa A., Buecker, Janet L., Pittman, Debra D., Kaufman, Randal J., Brown, Eugene, Shoemaker, Charles, Orr, Elizabeth C., Amphlett, Godfrey W., Foster, W. Barry, Coe, Mary Lou, Knutson, Gaylord J., Fass, David N., Hewick, Rodney M. |
| المصدر: | Nature; November 1984, Vol. 312 Issue: 5992 p342-347, 6p |
| مستخلص: | A complete copy of the mRNA sequences encoding human coagulation factor VIII:C has been cloned and expressed. The DNA sequence predicts a single chain precursor of 2,351 amino acids with a relative molecular mass (Mr) 267,039. The protein has an obvious domain structure, contains sequence repeats and is structurally related to factor V and ceruloplasmin. |
| قاعدة البيانات: | Supplemental Index |
| تدمد: | 00280836 14764687 |
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| DOI: | 10.1038/312342a0 |