Academic Journal

5‑Phenyl-1,3,4-oxadiazol-2(3H)‑ones Are Potent Inhibitors of Notum Carboxylesterase Activity Identified by the Optimization of a Crystallographic Fragment Screening Hit.

التفاصيل البيبلوغرافية
العنوان: 5‑Phenyl-1,3,4-oxadiazol-2(3H)‑ones Are Potent Inhibitors of Notum Carboxylesterase Activity Identified by the Optimization of a Crystallographic Fragment Screening Hit.
المؤلفون: Mahy, William, Willis, Nicky J., Zhao, Yuguang, Woodward, Hannah L., Svensson, Fredrik, Sipthorp, James, Vecchia, Luca, Ruza, Reinis R., Hillier, James, Kjær, Svend, Frew, Sarah, Monaghan, Amy, Bictash, Magda, Salinas, Patricia C., Whiting, Paul, Vincent, Jean-Paul, Jones, E. Yvonne, Fish, Paul V.
المصدر: Journal of Medicinal Chemistry; 11/12/2020, Vol. 63 Issue 21, p12942-12956, 15p
قاعدة البيانات: Supplemental Index
الوصف
تدمد:00222623
DOI:10.1021/acs.jmedchem.0c01391