Academic Journal

Desensitization to natalizumab: clinical and immunological observations.

التفاصيل البيبلوغرافية
العنوان: Desensitization to natalizumab: clinical and immunological observations.
المؤلفون: Ribizzi, Giuseppe, Bignardi, Donatella, Farinini, Daniele, Sassos, Davide, Gentile, Riccarda, Arecco, Daniela, Rizzi, Domenica, Voltolini, Susanna, Serrati, Carlo
المصدر: Multiple Sclerosis Journal; Mar2013, Vol. 19 Issue 3, p376-377, 2p
مصطلحات موضوعية: MULTIPLE sclerosis, NATALIZUMAB, DESENSITIZATION (Psychotherapy), IMMUNOGLOBULIN E, NEUROLOGY, PATIENTS
مستخلص: The article presents a case study of a 36-year-old male patient with multiple sclerosis, who previously underwent disease-modifying therapy (DMT), shifted to natalizumab (NZB) therapy due to rapid neurological deterioration. It showed a negative result of the skin prick test with NZB solution, however, the intradermal test revealed a positive result. It concluded that a progressive reduction of total immunoglobulin E (IgE) levels could be associated to a successful desensitization to NZB.
قاعدة البيانات: Complementary Index
الوصف
تدمد:13524585
DOI:10.1177/1352458512448269