التفاصيل البيبلوغرافية
| العنوان: |
Immunophenotypic Shift in a Case of Mycosis Fungoides With Vitreous Invasion. |
| المؤلفون: |
Lois, Noemi, Hiscott, Paul S., Nash, John, Wong, David |
| المصدر: |
Archives of Ophthalmology; Dec2000, Vol. 118 Issue 12, p1692, 3p |
| مصطلحات موضوعية: |
MYCOSIS fungoides, T cells, LYMPHOMAS, CD antigens, IMMUNOPHENOTYPING |
| مستخلص: |
The case of an 82-year-old man who developed intraocular extension from mycosis fungoides, a cutaneous T-cell lymphoma, is presented. The patient died soon after intraocular involvement occurred. Immunohistochemistry of a skin biopsy, taken early in the course of the disease, disclosed a predominance of T cells with a helper/inducer phenotype (CD4[sup +]). However, an intraocular infiltrate obtained 7 years later contained mostly T cells with a suppressor/cytotoxic phenotype (CD8[sup +]). The occurrence of ocular invasion, the change in immunophenotype, and the predominant proliferation of CD8[sup +] lymphocytes may have been related to the poor outcome in this patient. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |