التفاصيل البيبلوغرافية
| العنوان: |
Value of autofluorescence bronchoscopy in patients with laryngeal cancer. |
| المؤلفون: |
Çetınkaya, E, Veyseller, B, Yildirim, Y S, Aksoy, F, Özgül, M A, Gençoğlu, A, Altin, S |
| المصدر: |
Journal of Laryngology & Otology; 02/01/2011, Vol. 125 Issue 2, p181-187, 7p |
| مصطلحات موضوعية: |
SQUAMOUS cell carcinoma, CANCER treatment, PRECANCEROUS conditions, LARYNGEAL cancer diagnosis, BRONCHOSCOPY, CANCER, LARYNGECTOMY, LONGITUDINAL method, LUNG tumors, MEDICAL screening, TRACHEOTOMY, PREDICTIVE tests, CROSS-sectional method, DIAGNOSIS |
| مستخلص: |
Background:Patients with squamous cell carcinoma of the head and neck constitute a high risk group for synchronous and metachronous tumours.Objective:This study aimed to investigate the usefulness of white light and autofluorescence bronchoscopy in the evaluation of pre-malignant and early neoplastic lesions in patients with laryngeal cancer, who are at high risk of concomitant lung cancer.Methods:This prospective, cross-sectional study included 30 patients who had undergone total laryngectomy for squamous cell carcinoma of the larynx. The tracheobronchial system was investigated for the presence of pre-malignant and malignant lesions, using a combination of white light and autofluorescence bronchoscopy. Biopsies were obtained from areas with a pathological appearance, and histopathological studies were performed.Results:All patients had a permanent tracheostomy. Light and autofluorescence bronchoscopy indicated that the tracheobronchial system was normal in 11 patients. A total of 27 biopsies was taken from the remaining 19 patients, and revealed invasive squamous cell carcinoma in one patient and pre-malignant changes in six.Conclusion:Bronchoscopy is a valuable and practical tool for screening patients at high risk of lung cancer, and requires minimal intervention especially in patients with a permanent tracheostomy. Of the various bronchoscopic techniques becoming available, autofluorescence bronchoscopy shows promise for the detection of pre-invasive malignant changes of the tracheobronchial system in patients previously operated upon for laryngeal cancer. [ABSTRACT FROM PUBLISHER] |
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| قاعدة البيانات: |
Complementary Index |