التفاصيل البيبلوغرافية
| العنوان: |
Does dietary protein reduce hip fracture risk in elders? The Framingham osteoporosis study. |
| المؤلفون: |
Misra, D., Berry, S. D., Broe, K. E., McLean, R. R., Cupples, L. A., Tucker, K. L., Kiel, D. P., Hannan, M. T. |
| المصدر: |
Osteoporosis International; Jan2011, Vol. 22 Issue 1, p345-349, 5p, 2 Charts |
| مصطلحات موضوعية: |
BONE fracture prevention, ANALYSIS of variance, CHI-squared test, CONFIDENCE intervals, DIET, HIP joint, MULTIVARIATE analysis, OSTEOPOROSIS, PROTEINS, REGRESSION analysis, T-test (Statistics), DISEASE incidence, PROPORTIONAL hazards models, DISEASE complications, OLD age |
| مصطلحات جغرافية: |
MASSACHUSETTS |
| مستخلص: |
Summary: Association between dietary protein and fracture risk is unclear. We examined association between energy-adjusted protein intake and hip fracture risk in elders. The risk of hip fracture was reduced in upper quartiles of protein intake when compared with lowest quartile. Introduction: Studies of the association between dietary protein intake and hip fracture risk are conflicting. Therefore, we examined protein intake and hip fracture risk in a population-based group of elderly men and women. Methods: Five hundred seventy-six women and 370 men from the Framingham Osteoporosis Study with no previous history of hip fracture completed Food Frequency Questionnaires. Energy-adjusted protein intake was evaluated as a continuous variable and as quartiles. Incidence rates and hazard ratios were calculated, adjusting for age, BMI, sex, and energy intake. Results: Among 946 participants (mean age 75 years), mean protein intake was found to be 68 gm/d. Increased protein intake was associated with a decreased risk of hip fracture compared to those in the lowest quartile of protein intake (Q2 HR = 0.70, Q3 HR = 0.56, and Q4 HR = 0.63; all p values ≥ 0.044), p for trend was 0.07. When a threshold effect was considered (Q2-4 vs Q1), intakes in the higher quartiles combined were associated with a significantly lower risk for hip fracture (HR = 0.63; p = 0.04). Conclusion: Our results are consistent with reduced risk of hip fracture with higher dietary protein intake. Larger prospective studies are needed to confirm and extend this finding in elderly men and women. [ABSTRACT FROM AUTHOR] |
|
Copyright of Osteoporosis International is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |