التفاصيل البيبلوغرافية
| العنوان: |
NUP98–HMGB3: a novel oncogenic fusion. |
| المؤلفون: |
Petit, A, Ragu, C, Della-Valle, V, Mozziconacci, M J, Lafage-Pochitaloff, M, Soler, G, Schluth, C, Radford, I, Ottolenghi, C, Bernard, O A, Penard-Lacronique, V, Romana, S P |
| المصدر: |
Leukemia (08876924); Mar2010, Vol. 24 Issue 3, p654-658, 5p, 2 Graphs |
| مصطلحات موضوعية: |
CANCER, BONE marrow, GENES, LEUKEMIA, CANCER genes, CHARTS, diagrams, etc. |
| مستخلص: |
The article discusses about the NUP98 promiscuou gene. It is involved in chromosomal aberrations with other genes in variety of human hematological malignancies. Study of overexpression in mouse bone marrow indicates that NUP98 induce leukemic transformation. The article reports about the involvement of NUP98 in the therapy related acute myeloblastic leukemia. The article also describes the process of NUP98-HMBG3 fusion. Various charts related to the experiment is presented. |
| قاعدة البيانات: |
Complementary Index |
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