Academic Journal

Cross-talk between cytokines and renin–angiotensin in hypothalamic paraventricular nucleus in heart failure: role of nuclear factor-κB.

التفاصيل البيبلوغرافية
العنوان: Cross-talk between cytokines and renin–angiotensin in hypothalamic paraventricular nucleus in heart failure: role of nuclear factor-κB.
المؤلفون: Yu-Ming Kang, Ying Ma, Carrie Elks, Jin-Ping Zheng, Zhi-Ming Yang, Francis, Joseph
المصدر: Cardiovascular Research; Sep2008, Vol. 79 Issue 4, p671-678, 8p
مصطلحات موضوعية: CYTOKINES, RENIN-angiotensin system, HYPOTHALAMUS, HEART failure, NF-kappa B
مستخلص: Aims: Nuclear factor-kappa B (NF-κB) is a potent inducer of pro-inflammatory cytokines (PIC) and oxidative stress in cardiovascular disease. In this study, we determined whether upregulation of NF-κB in the hypothalamic paraventricular nucleus (PVN) contributed to neurohumoral excitation either directly, or via interaction with the renin–angiotensin system (RAS), in heart failure (HF). [ABSTRACT FROM PUBLISHER]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:00086363
DOI:10.1093/cvr/cvn119