التفاصيل البيبلوغرافية
| العنوان: |
Relationship between lactate albumin ratio and mortality in patients with ischemia and non-obstructive coronary artery disease (INOCA). |
| المؤلفون: |
Aydin, Sidar Siyar, Aydemir, Selim, Ozmen, Murat, Gulcu, Oktay |
| المصدر: |
Annals of Medical of Research; Jan2025, Vol. 32 Issue 1, p8-13, 6p |
| مستخلص: |
Aim: Ischemia with non-obstructive coronary artery disease (INOCA) is when there is myocardial ischemia without occlusive coronary artery disease. Over time, this could result in a reduced quality of life, frequent hospital visits, and a higher risk of cardiovascular-related deaths. Diagnosis, management, and prognosis of INOCA pose challenges. Lactatealbumin ratio (LAR) has been associated with mortality from many cardiovascular diseases. The study examined the link between LAR and mortality in patients with INOCA. Materials and Methods: The study analyzed data from 987 patients diagnosed with ischemia through myocardial perfusion imaging using single photon emission computed tomography (MPI-SPECT) at our center between 2017 and 2023. After applying the exclusion criteria, we included 279 patients in the study. Medical histories, laboratory parameters, and patient death information were recorded. Results: The mean follow-up time was 20547 days. Mortality occurred in 5% of patients (14 patients). Patients were divided into two groups: mortality and non-mortality. The LAR was 0.65 ± 0.26 in the non-mortality group and 1.05 ± 0.32 in the mortality group, indicating a meaningful disparity between the two groups (p=0.017). Cox regression analysis was conducted to determine mortality predictors. In INOCA patients, mortality was independently predicted by age and LAR (p=0.03, and p=0.005, respectively). To evaluate the efficacy of LAR in predicting mortality, we executed the Receiver Operating Characteristic (ROC) analysis. The examination revealed an area under the curve (AUC) of 0.689 (0.519-0.858), a cut-off of 0.656, a sensitivity of 57.1%, and a specificity of 52.8% (p=0.017). Conclusion: Our study found that LAR performs as an independent predictor of mortality in patients with INOCA. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |