Academic Journal

Editorial: TRLs (triglycerides-rich lipoproteins): a new target for atherosclerosis.

التفاصيل البيبلوغرافية
العنوان: Editorial: TRLs (triglycerides-rich lipoproteins): a new target for atherosclerosis.
المؤلفون: Dong, Mei, Yang, Yunlong, Hosaka, Kayoko, Zhang, Yun, Zhao, Yuxia
المصدر: Frontiers in Endocrinology; 2025, p1-3, 3p
مصطلحات موضوعية: LIPOPROTEIN lipase, HDL cholesterol, ANGIOPOIETIN-like proteins, LOW density lipoproteins, HEART metabolism disorders, NIACIN, CHYLOMICRONS, CHOLESTERYL ester transfer protein, MUSCLE mass
مستخلص: The editorial in Frontiers in Endocrinology discusses triglycerides-rich lipoproteins (TRL) as a new target for atherosclerosis, particularly in diabetic populations. The accumulation of TRLs and their cholesterol-enriched remnants is linked to atherogenesis, with Apo CIII and ANGPTL3 identified as key targets for therapeutic strategies. Various studies highlight the importance of understanding TRL metabolism and residual cholesterol in relation to metabolic disorders and cardiovascular diseases, suggesting potential new clinical monitoring indicators and risk assessment tools. Research focuses on developing novel drugs to reduce TRLs and improve patient prognosis, emphasizing the need for standardized residue detection methods in clinical practice. [Extracted from the article]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:16642392
DOI:10.3389/fendo.2024.1540602