التفاصيل البيبلوغرافية
| العنوان: |
Efficacy of microneedling combined with calcipotriol plus betamethasone in the treatment of vitiligo. |
| المؤلفون: |
Manzoor, Saima, Sadia, Anum, Siddique, Madiha, Mumtaz, Ayesha, Azfar, Nadia Ali, Hayat, Rabia |
| المصدر: |
Journal of Pakistan Association of Dermatologists; 2024 Supplement, Vol. 34, pS25-S30, 6p |
| مصطلحات موضوعية: |
MICRONEEDLING, BETAMETHASONE, DISEASE duration, VITILIGO, WOMEN patients |
| مستخلص: |
Objective To assess the outcome of microneedling combined with calcipotriol plus betamethasone (measured by mean change in VASI) in the treatment of vitiligo. Methods This study involved 57 patients of both genders aged between 15-45 years presenting with vitiligo enrolled after taking informed written consents. These patients were assessed by VASI score before starting treatment. Treatment was given in the form of microneedling combined with calcipotriol plus betamethasone. VASI score was reassessed 2 weeks after 3 months of treatment. Outcome variable was mean change in VASI score which was measured by subtracting the follow-up VASI score from that at baseline and compared across various subgroups of studied patients. Results Mean age of the patients was 26.4±8.9 years. There were 26 (45.6%) male and 31 (54.4%) female patients. Mean duration of disease was 4.56±1.71 years. Family history of vitiligo was present in 16 (28.1%) patients. The mean change in VASI score from baseline was 39.65±4.97. Mean change in VASI score across various subgroups of patients had insignificant difference (p-value> 0.05). Conclusion Microneedling combined with calcipotriol and betamethasone was associated with considerable mean change in VASI score in vitiligo patients which owing to safety and simplicity of treatment advocates its preferred use in managing such patients in future dermatological practice. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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