التفاصيل البيبلوغرافية
| العنوان: |
Simultaneous Determination of Penicillin G and Cephalexin in Real Samples by Electrochemical Method Based on Modified Carbon Paste Electrode by CoFe2O4/Gr Nanocomposite. |
| المؤلفون: |
Almasi, Mohammad Hossein, Baezzat, Mohammad Reza, Tavakkoli, Nahid, Soltani, Nasrin |
| المصدر: |
Analytical & Bioanalytical Chemistry Research (TPR); Jan2025, Vol. 12 Issue 1, p85-100, 16p |
| مصطلحات موضوعية: |
FOURIER transform infrared spectroscopy techniques, PENICILLIN G, ANTIBIOTIC residues, CARBON electrodes, CYCLIC voltammetry, HONEY |
| مستخلص: |
Residues of antibiotics can be present in animal-based food products or beekeeper treatments. It is essential to detect and monitor these antibiotic residues in food materials to minimize any negative effects caused by their presence. In this research, a cost-effective, sensitive sensor was created for the simultaneous electrochemical determination of penicillin G and cephalexin. This sensor used a modified carbon paste electrode (CPE) with CoFe2O4/graphene (Gr) nanomaterials with an abbreviation (CPE/CoFe2O4/Gr). The CoFe2O4 magnetic nanoparticles were characterized using techniques such as Fourier transform infrared spectroscopy (FT-IR) and X-ray diffraction spectroscopy (XRD). The CPE/CoFe2O4/Gr surface was checked by cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), and scanning electron microscopy (SEM) methods. As well, differential pulse voltammetry (DPV) was used to present the electrocatalytic effect of the modifier on the oxidation of the analytes. The sensor displayed a linear wide-ranging for the determination of penicillin (0.5-50 µM) and cephalexin (0.1-60 µM) in a phosphate buffer solution at pH 8.0. The limit of detection (LOD) for penicillin and cephalexin was 0.026 and 0.023 µM, respectively. Sensitivity was obtained for penicillin 5.938 µA/(µM⋅cm²) and for cephalexin 4.91 µA/(µM⋅cm²). It also demonstrated good reproducibility, repeatability, and long-term stability. The penicillin and cephalexin were successfully determined by this sensor in real samples with acceptable recoveries of 96.20-101.02% and 95.40-101.07% and RSD% of less than 3%. Investigations up to the time of writing the article indicate a new and unique method for the simultaneous detection of cephalexin and penicillin in food, especially in milk and honey. [ABSTRACT FROM AUTHOR] |
|
Copyright of Analytical & Bioanalytical Chemistry Research (TPR) is the property of Analytical & Bioanalytical Chemistry Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |