Academic Journal

Video‐assisted thoracoscopic surgery versus open thoracotomy for resection of lung metastasis—A meta‐analysis of reconstructed time‐to‐event data.

التفاصيل البيبلوغرافية
العنوان: Video‐assisted thoracoscopic surgery versus open thoracotomy for resection of lung metastasis—A meta‐analysis of reconstructed time‐to‐event data.
المؤلفون: Passos, Felipe S., Bregion, Pedro B., Fazzini, Luca, Kirov, Hristo, Sandhaus, Tim, von Samson, Patrick, Doenst, Torsten, Caldonazo, Tulio
المصدر: Thoracic Cancer; Dec2024, Vol. 15 Issue 34, p2401-2407, 7p
مصطلحات موضوعية: VIDEO-assisted thoracic surgery, DESCRIPTIVE statistics, ODDS ratio, THORACOSCOPY, CONFIDENCE intervals, PROPORTIONAL hazards models, OVERALL survival
مستخلص: This study aimed to conduct a systematic review and meta‐analysis comparing video‐assisted thoracoscopic surgery (VATS) and open thoracotomy (OT) in the context of pulmonary metastasectomy. Three databases were assessed. The primary outcome was overall survival. The secondary outcomes were recurrence‐free survival, ipsilateral recurrence, and hospital length of stay (LOS). Hazard ratios (HRs), odds ratios (ORs), and mean difference (MD) with 95% confidence intervals (CIs) were calculated. Reconstruction of time‐to‐event data and sensitivity analyses were performed for the primary endpoint. After screening, 11 studies were included encompassing 2159 patients undergoing lung metastasectomy (VATS: 827; OT: 1332). Compared to OT, patients who underwent VATS had higher overall survival rates (HR 0.75; 95% CI 0.67–0.85; p < 0.01), no significant difference in recurrence‐free survival (HR 1.07; 95% CI 0.88–1.29; p = 0.48), shorter hospital LOS (MD −1.99 days; 95% CI −2.59 to −1.39; p < 0.01), and no significant difference in ipsilateral recurrence rates (OR 0.86; 95% CI 0.52–1.42; p = 0.56). For patients undergoing pulmonary metastasectomy, VATS strategy is associated with higher survival rates and reduced hospital LOS when compared with OT. Moreover, metastasis recurrence does not seem to be associated with long‐term mortality in this population. [ABSTRACT FROM AUTHOR]
Copyright of Thoracic Cancer is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
قاعدة البيانات: Complementary Index
الوصف
تدمد:17597706
DOI:10.1111/1759-7714.15473