التفاصيل البيبلوغرافية
| العنوان: |
APAtizer: a tool for alternative polyadenylation analysis of RNA-Seq data. |
| المؤلفون: |
Sousa, Bruno, Bessa, Maria, Mendonça, Filipa L de, Ferreira, Pedro G, Moreira, Alexandra, Pereira-Castro, Isabel |
| المصدر: |
Bioinformatics; Nov2024, Vol. 40 Issue 11, p1-4, 4p |
| مصطلحات موضوعية: |
GENE expression, SOURCE code, GENE ontology, STATISTICAL correlation, RNA sequencing |
| مستخلص: |
Summary APAtizer is a tool designed to analyze alternative polyadenylation events on RNA-sequencing data. The tool handles different file formats, including BAM, htseq, and DaPars bedGraph files. It provides a user-friendly interface that allows users to generate informative visualizations, including Volcano plots, heatmaps, and gene lists. These outputs allow the user to retrieve useful biological insights such as the occurrence of polyadenylation events when comparing two biological conditions. In addition, it can perform differential gene expression, gene ontology analysis, visualization of Venn diagram intersections, and correlation analysis. Availability and implementation Source code and example case studies for APAtizer are available at https://github.com/GeneRegulationi3S/APAtizer/. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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