التفاصيل البيبلوغرافية
العنوان: |
Review of Novel Surgical, Radiation, and Systemic Therapies and Clinical Trials in Glioblastoma. |
المؤلفون: |
Valerius, Allison R., Webb, Lauren M., Thomsen, Anna, Lehrer, Eric J., Breen, William G., Campian, Jian L., Riviere-Cazaux, Cecile, Burns, Terry C., Sener, Ugur |
المصدر: |
International Journal of Molecular Sciences; Oct2024, Vol. 25 Issue 19, p10570, 28p |
مصطلحات موضوعية: |
BRAIN tumors, EXPERIMENTAL design, GLIOBLASTOMA multiforme, GLIOMAS, SURGICAL excision |
مستخلص: |
Glioblastoma (GBM) is the most common malignant primary brain tumor in adults. Despite an established standard of care including surgical resection, radiation therapy, and chemotherapy, GBM unfortunately is associated with a dismal prognosis. Therefore, researchers are extensively evaluating avenues to expand GBM therapy and improve outcomes in patients with GBM. In this review, we provide a broad overview of novel GBM therapies that have recently completed or are actively undergoing study in clinical trials. These therapies expand across medical, surgical, and radiation clinical trials. We additionally review methods for improving clinical trial design in GBM. [ABSTRACT FROM AUTHOR] |
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قاعدة البيانات: |
Complementary Index |