التفاصيل البيبلوغرافية
| العنوان: |
Genome Characterization of a Tailam Virus Discovered in Brown Rats in Yunnan Province, China. |
| المؤلفون: |
Fan, Yayu, Hou, Yutong, Duan, Yimeng, Li, Qian, Le, Xiang, Jiang, Jinyong, Xu, Xiang, Wang, Binghui, Xia, Xueshan |
| المصدر: |
Vector-Borne & Zoonotic Diseases; Oct2024, Vol. 24 Issue 10, p689-693, 5p |
| مصطلحات موضوعية: |
VIRUS diversity, RATTUS norvegicus, PARAMYXOVIRUSES, RODENTS, VIRAL transmission |
| مستخلص: |
Paramyxoviridae is one of the most well known and largest virus families, including some animal and human pathogens, such as the Hendra, Nipah, and Rinderpest viruses, with a high potential for the emergence of human diseases. Based on recent phylogenetic analyses, two new genera (Narmovirus and Jeilongvirus) have been described. The newly recognized genus Jeilongvirus has rapidly increased in number and has grown to 15 species from 7 a few years ago. However, little is known about the diversity, host range, or evolution of Jeilongvirus. As a well-known host reservoir for many pathogens, rodents have always been the focus for characterizing their pathogenic potential. In this study, we isolated a Tailam virus strain (RN-JH-YN-2022-1) belonging to the genus Jeilongvirus from Rattus norvegicus in Yunnan Province, China. The virus presented a near-complete genome (19,046 nucleotides). Similar to other members of the genus Jeilongvirus, the genome of RN-JH-YN-2022-1 contains eight basic genes (3′-N-P/V/C-M-F-SH-TM-G-L-5′) with 88.88% sequence identity to Tailam virus (TL8K). Additionally, we discuss the pattern of genus Jeilongvirus diversity and the possible route of spread of the Tailam virus, which could provide new clues into the host range, virus diversity, and geographical distribution of the genus Jeilongvirus. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |