التفاصيل البيبلوغرافية
| العنوان: |
Periodontal tissue susceptibility to glycaemic control in type 2 diabetes. |
| المؤلفون: |
Inoue, Moe, Sakanaka, Akito, Katakami, Naoto, Furuno, Masahiro, Nishizawa, Hitoshi, Omori, Kazuo, Taya, Naohiro, Ishikawa, Asuka, Mayumi, Shota, Tanaka Isomura, Emiko, Takeuchi, Hiroki, Amano, Atsuo, Shimomura, Iichiro, Fukusaki, Eiichiro, Kuboniwa, Masae |
| المصدر: |
Diabetes, Obesity & Metabolism; Oct2024, Vol. 26 Issue 10, p4684-4693, 10p |
| مصطلحات موضوعية: |
GLYCEMIC control, TYPE 2 diabetes, DIABETES complications, ACETOACETIC acid, BLOOD sugar |
| مستخلص: |
Aim: To assess the direct effect of intensive glycaemic control on periodontal tissues in patients with diabetes mellitus. Materials and Methods: Twenty‐nine patients with type 2 diabetes were enrolled and hospitalized to receive a 2‐week intensive glycaemic control regimen. We observed and analysed the systemic and oral disease indicators before and after treatment and clarified the indicators related to periodontal inflammation. Results: A significant reduction in glycaemic and periodontal parameters, including glycated albumin levels and periodontal inflamed surface area (PISA), was observed after treatment. The changes in PISA per tooth, indicative of periodontal healing, exhibited a bimodal distribution; the patients were divided into two groups on this basis. Correlations were observed between the changes in PISA per tooth and fasting plasma glucose, acetoacetic acid, and beta‐hydroxybutyrate levels in the PISA‐improved group. Significantly lower levels of C‐peptide, coefficient of variation of R‐R interval, and ankle‐brachial pressure index were observed before treatment in the PISA non‐improved group. Conclusions: Glycaemic control treatment can effectively improve periodontitis in patients with type 2 diabetes, even in the absence of specific periodontal treatments. However, the periodontal responsiveness to glycaemic control treatment depends on the systemic condition of the patient. [ABSTRACT FROM AUTHOR] |
|
Copyright of Diabetes, Obesity & Metabolism is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |